For CMC and formulation
Stability package and shelf life take days, DoE lives in Excel.
Here is what that path looks like today, and what it looks like with validated tools inside your AI assistant.
Today
- The stability plan lives in Word, the evaluation in Excel.
- Arrhenius fit and shelf life are recomputed by whoever knows the sheet.
- DoE plans get copied from old projects, the power question stays open.
- Solubility and salt form are tried out, not narrowed down first.
With CovaSyn
- ICH-compliant plan, Arrhenius fit and shelf-life band come from the same window.
- For the experiment you get an RSM design with power analysis before material is consumed.
- pH curves, miscibility and antisolvent strategies narrow the salt form beforehand.
- Multi-objective optimisation and robustness checks continue on the same data.
The calculation is traceable instead of buried in a grown spreadsheet. What goes into the dossier is still a human decision.
The tools behind it
Covastab
20 functionsICH stability models, Arrhenius fits, shelf-life predictions.
Covadoe
21 functionsDesign of Experiments with RSM, power analysis, optimisation and ready-made templates.
Covasolve
9 functionsSolubility prediction, miscibility, pH curves and antisolvent strategies.
Covaopt
21 functionsMulti-objective optimisation, robustness, drift detection, model training.
Frontier LLMs reach 14 to 41 percent on chemistry. With CovaSyn MCP attached: 76 to 92 percent.
Peer-reviewed MolecularIQ benchmark (ICLR 2026). 3,540 verified chemistry tasks, four frontier models. Three reach 85 to 92 %; the cheapest (Gemini 3.5 Flash) lands at 76 %.
Create an account and try the tools right away. No credit card.