Sketch
Research-grade structure editor (Ketcher 3.12). Clean, journal-ready structures, unambiguous and reusable as SMILES.
CovaSketch · Chemistry Workbench
Sketch the structure.
Tell the story.
CovaSketch pairs a research-grade chemical sketcher with the full CovaSyn analytics suite. Properties, spectra, retrosynthesis and stability are one right-click away. The molecule-first lab notebook on the deterministic tool layer behind the CovaSyn MCP server.
- Ketcher 3.12, journal-ready
- Deterministic, no hallucination
- GDPR · EU data residency
Features
What CovaSketch does
Four capabilities, one workspace. From a sketch to a documented, defensible answer.
Predict
pKa, NMR, LogP and ADMET on demand. Computed deterministically by the CovaSyn analytics suite, not hallucinated.
Search
Find trade names and patents for the structure you drew via PubChem, without leaving the context.
Reason
Claude with tool-use, inline. Ask about the structure and get traceable, defensible answers.
Workflow
From a sketch to an answer you can trust
01
Sketch
Draw the structure right in your browser. CovaSketch canonicalizes it to SMILES automatically: clean, unambiguous, ready to use.
02
Analyze
Properties, spectra, retrosynthesis and stability are one right-click away, computed by the full CovaSyn analytics suite.
03
Document
Every step lands in the notebook: journal-ready, reproducible, audit-ready. “The AI said so” becomes a traceable record.
Analytics
The analytics behind the right-click
One drawn structure, the full CovaSyn analytics suite. Every domain covered by a validated, deterministic lab-stack tool.
CovaPhysChem
Physicochemistry
pKa, LogP and physicochemical properties.
CovaSolv
Solubility & formulation
Solubility, miscibility, pH curves, antisolvent.
CovaChem
ADMET & safety
ADME, druglikeness, ICH M7, Tox21, structural alerts.
CovaSyn analytics
Spectra
Predict NMR, MS and IR for the structure you drew.
CovaStab
Stability
Arrhenius kinetics, shelf-life, OOS/OOT.
CovaDock
Docking & binding
Docking, binding poses, refinement.
Who it's for
Built for everyday lab work
A tool for everyone who works with structures, from the first idea to regulatory documentation.
Medicinal chemistry & drug discovery
Draw candidates, assess ADMET and druglikeness early, plan retrosynthesis.
Formulation & process
Keep solubility, stability, shelf-life and physicochemical properties in view.
Analytics & regulatory
Predict spectra, verify identity and purity, document ICH M7 risks defensibly.
Why CovaSketch
Not another drawing tool. A defensible workspace.
Deterministic
Same structure, same result. No hallucination.
Reproducible & audit-ready
Every step version-pinned and defensible, ICH-aligned.
One workspace
Sketch, compute, search and document without tool-switching.
EU hosting & GxP-ready
GDPR-aligned, built for regulated environments.
FAQ
Frequently asked questions
- What is CovaSketch?
- A molecule-first lab notebook: sketch a structure, analyze it with the CovaSyn analytics suite and document it reproducibly, on the deterministic tool layer behind the CovaSyn MCP server.
- Do I need an account?
- Yes. You can create a free account or log in with your existing MCP access and start testing the sketcher right away.
- Which editor does CovaSketch use?
- The research-grade Ketcher 3.12 editor with journal-ready output. Structures are unambiguous and reusable as SMILES.
- Are the results reliable?
- Yes. Every value is computed deterministically (same input, same result), not hallucinated by an LLM. Each step is reproducible and audit-ready.
- What can I analyze?
- pKa, LogP, NMR, ADMET, ICH M7, stability, retrosynthesis, docking and more. All via the CovaSyn lab stack, one right-click away.
- Where does my data run?
- On the CovaSyn platform: GDPR-aligned, EU data residency and GxP-ready for regulated environments.
Get started
Draw your first structure.
CovaSketch runs on the CovaSyn platform. Sign up and try the sketcher, or log in if you already have MCP access.