CovaSyn

For QA and regulatory

ICH M7 assessment takes weeks, nitrosamine risk without a fast first picture.

Here is what that path looks like today, and what it looks like with validated tools inside your AI assistant.

Today

  • The ICH M7 assessment passes through several hands and several weeks.
  • Structural alerts get looked up, the rationale is written by hand.
  • On a nitrosamine suspicion the fast first picture is missing.
  • For the inspection you must show how an assessment came about.

With CovaSyn

  • ICH M7 mutagenicity screening returns a first classification including structural alerts.
  • Suspect impurities are checked against mass spectra and fragment annotation.
  • Triage says early what is harmless and what needs a real assessment.
  • Input, tool version, configuration and result are logged for every call.

The assessment stays yours. CovaSyn provides the first pass and the trail that keeps it traceable.

The tools behind it

Covatox

ICH M7 mutagenicity screening, Tox21, CYP450, structural alerts, ADMET triage.

Covams

Mass spectra, formula prediction, fragment annotation, impurity profiling.

Independent benchmark · MolecularIQ

Frontier LLMs reach 14 to 41 percent on chemistry. With CovaSyn MCP attached: 76 to 92 percent.

Independent MolecularIQ benchmark (arXiv:2601.15279). 3,540 verified chemistry tasks, four frontier models. Three reach 85 to 92 %; the cheapest (Gemini 3.5 Flash) lands at 76 %.

85.4 %
Haiku 4.5 + MCP
21.2 % baseline
91.5 %
Opus 4.7 + MCP
40.8 % baseline
89.9 %
GPT-5.5 + MCP
22.3 % baseline
75.7 %
Gemini 3.5 + MCP
13.7 % baseline
Full benchmark data
Pareto frontier: accuracy vs cost per question
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CovaSyn for QA and regulatory: ICH M7, mutagenicity, nitrosamines, structural alerts, impurity, audit trail | CovaSyn