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CovaSyn

OFAT, DoE or adaptive? Choosing the experiment strategy for process development

When classical DoE wins, from how many factors an adaptive approach needs fewer experiments, and how many experiments per round pay off. Measured on 5,040 simulated campaigns and three public reaction screens.

  • 01Up to 4 factors: where classical DoE came out ahead
  • 02From 8 factors: 1.3 to 3.1 times fewer experiments to the DoE result
  • 03Experiments per round: 4 instead of 28 rounds for the same target
  • 04Decision guide, case studies and the limits of the study

PDF, 24 pages, A4

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