From the lab
A first risk picture before toxicology
A new active ingredient is on the table. Before toxicology starts, the team needs a first risk picture.
How CovaSyn solved it
The evaluation shows every structural alert with its evidence and states where it is uncertain; the decision stays with your experts.
Where the result reaches its limits: A C-F bond is a poor alkylating agent. This is exactly where the toxicologist decides.
The values
| Mutagenicity alerts | Alkyl fluoride alert, statistical model negative |
|---|---|
| Evidence behind the alert | Odds ratio 1.64 in the Ames dataset |
| Other structural flags | 6 alerts, 3 of them hERG motifs, none with high evidence |
Free PDF
Results you can rely on
Our beginner's guide for chemistry, pharma and biotech: how to tell an estimate from a calculation, seven questions to ask of every result and six questions to ask every provider. 8 pages.
Next step
Is a similar case waiting in your lab?
Talk it through with us, 30 minutes on Microsoft Teams. Afterwards you know whether we take it on and which data we need.